chanzuckerberg/py2rely

Tools for Running Relion5 Sub-Tomogram Refinement Through CLI

Python

Other

py2rely is a Python-based tool that simplifies and accelerates RELION sub-tomogram averaging workflows on SLURM-based HPC clusters. It integrates with AreTomo for tilt series alignment and copick for particle coordinate storage, enabling automated job preparation, classification, and refinement. Designed for researchers in cryo-electron tomography, it streamlines rapid iteration and validation of particle picking strategies for structure determination.

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